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It is classified as a vitamin, as it is an essential nutrient for the human body and is regularly obtained from the food we eat

One clinical trial of pregnant and lactating mothers found that mothers needed to consume 3 times the recommended amounts of vitamin B12 to maintain adequate vitamin B12 status throughout pregnancy and lactation

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To date, the term bio-corona has been introduced as an alternative to protein corona to more accurately represent the complex array of biomolecular components present in biological fluids to which nanoparticles are exposed ( in vivo biological properties of nanoparticles remains a major challenge for the rational design of nanomaterials for clinical applications